Taniraleucel

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human placental hematopoietic stem cells (HSCs) and expressing the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating, antineoplastic and antiviral activities. Upon infusion of taniraleucel, these cells are able to recognize tumor cells as well as virally-infected cells, secrete perforins, granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells.

**Synonyms:** - Allogeneic CD56+/CD3- Natural Killer Cells CYNK-001 - Allogeneic CD56-positive CD3-negative Natural Killer Cells CYNK-001 - Allogeneic Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells CYNK-001 - CD56+/CD3- NK Cells CYNK-001 - CYNK 001 - CYNK-001 - CYNK001 - Cord Blood-derived Expanded NK Cells PNK-007 - Cord Blood-derived Expanded Natural Killer Cells PNK-007 - Human CB-derived Natural Killer Cells PNK-007 - Human Placental HSC-derived CD56+/CD3- NKs CYNK-001 - Natural Killer Cells CYNK-001 - PNK 007 - PNK-007 - PNK007 - TANIRALEUCEL