Rett Syndrome Severity Scale Clinical Classification

**Semantic type:** Intellectual Product

**Definition:** A seven-item ratings scale developed by Hoffbuhr et al. 2001 that utilizes a four-point Likert scale to assess the severity of Rett Syndrome clinical presentation. The measured parameters include frequency and manageability of seizures, respiratory irregularities, scoliosis, ability to walk, hand use, speech, and sleep problems.

**Synonyms:** - RETT1 - RSSS - RSSS