Glucose-6-Phosphate Isomerase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a cytoplasmic homodimer and has a secreted monomeric form that either exhibits cytokine activity or can function as a neurotrophic factor.

**Synonyms:** - AMF - Autocrine Motility Factor - D-Glucose-6-Phosphate Ketol-Isomerase - EC 5.3.1.9 - GPI - Glucose Phosphate Isomerase - Glucosephosphate Isomerase - Hexose Monophosphate Isomerase - Hexosephosphate Isomerase - NLK - Neuroleukin - Oxoisomerase - PGI - PHI - Phosphoglucose Isomerase - Phosphohexomutase - Phosphohexose Isomerase - Phosphosaccharomutase - SA-36 - Sperm Antigen 36 - Sperm Antigen-36