T-Cell Receptor Gamma-Delta

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Receptor

**Definition:** A heterodimeric complex comprised of the T-cell receptor gamma and delta chain proteins, which are linked by interchain disulfide bonds. This membrane bound complex is expressed on the surface of a small percentage of T-lymphocytes and is involved in the recognition of antigenic lipids, peptide antigens, and peptides presented by major histocompatibility (MHC) proteins. The gamma/delta dimer associates with the CD3 protein complex, which promotes ligand-dependent signaling.

**Synonyms:** - T-Cell Receptor Gamma Delta - T-Cell Receptor Gamma/Delta - T-Cell Receptor, Gamma-Delta - TCR Gamma-Delta - TCR Gamma/Delta