FOS Family Gene

**Semantic type:** Gene or Genome

**Definition:** FOS Family Genes encode nuclear leucine zipper FOS Family Proteins (FOS, FOSB, FOSL1, and FOSL2) that can dimerize with JUN Family proteins and bind DNA as the AP-1 transcription factor complex to regulate transcription in cell proliferation, differentiation, and transformation. (NCI)

**Synonyms:** - FOS Gene