Inactivating KMT2D Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the KMT2D gene that inhibits expression or results in the translation of either low-activity or inactive forms of the histone-lysine N- methyltransferase 2D protein.

**Synonyms:** - Inactivating ALR Gene Mutation - Inactivating CAGL114 Gene Mutation - Inactivating KABUK1 Gene Mutation - Inactivating KMS Gene Mutation - Inactivating KMT2D Mutation - Inactivating Lysine (K)-Specific Methyltransferase 2D Gene Mutation - Inactivating Lysine Methyltransferase 2D Gene Mutation - Inactivating MLL2 Gene Mutation - Inactivating MLL4 Gene Mutation - Inactivating Myeloid/Lymphoid or Mixed-Lineage Leukemia 2 Gene Mutation - Inactivating TNRC21 Gene Mutation - KMT2D Gene Inactivation - KMT2D Inactivating Gene Mutation - KMT2D Inactivating Mutation - KMT2D Inactivation - KMT2D Loss of Function Gene Mutation - KMT2D Loss of Function Mutation - Loss of Function KMT2D Gene Mutation - Loss of Function KMT2D Mutation