IFITM3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IFITM3 wild-type allele is located in the vicinity of 11p15.5 and is approximately 8 kb in length. This allele, which encodes interferon-induced transmembrane protein 3, plays a role in the inhibition of viral fusion with host cells. Mutation of the gene is associated with increased susceptibility to severe influenza.

**Synonyms:** - 1-8U - DSPA2b - IP15 - Interferon Induced Transmembrane Protein 3 (1-8U) Gene - Interferon Induced Transmembrane Protein 3 wt Allele