T4 Endonuclease V

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** A DNA repair enzyme from bacteriophage T4. It catalyzes the first reaction step of the excision repair pathway to remove pyrimidine-dimers produced within duplex DNA by UV irradiation. It has been incorporated into a topical lotion for treatment of xeroderma pigentosum.

**Synonyms:** - Endonuclease V - Endonuclease V - T4 Endonuclease 5 - T4N5