Non-Synonymous TP53 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence in the TP53 gene that encodes an amino acid substitution in the cellular tumor antigen p53 protein.

**Synonyms:** - Non-Synonymous LFS1 Gene Mutation - Non-Synonymous Li-Fraumeni Syndrome Gene Mutation - Non-Synonymous P53 Gene Mutation - Non-Synonymous TP53 Mutation - Non-Synonymous TRP53 Gene Mutation - Non-Synonymous Tumor Protein p53 Gene Mutation - Non-Synonymous p53 Mutation - Non-synonymous TP53 Gene Mutation - TP53 Gene Missense Mutation - TP53 Missense Mutation - p53 Missense Mutation