NLRC4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NLRC4 wild-type allele is located in the vicinity of 2p22.3 and is approximately 41 kb in length. This allele, which encodes NLR family CARD domain-containing protein 4, plays a role in immunity and apoptosis. Mutation of the gene is associated with familial cold autoinflammatory syndrome 4 and autoinflammation with infantile enterocolitis.

**Synonyms:** - AIFEC - CARD12 - CLAN - CLAN1 - CLANA - CLANB - CLANC - CLAND - CLR2.1 - Caspase Recruitment Domain Family, Member 12 Gene - FCAS4 - IPAF - NLR Family CARD Domain Containing 4 wt Allele - NLR Family, CARD-Containing 4 Gene - NOD-Like Receptor C4 Gene - Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat and CARD Domain Containing 4 Gene - UNQ6189/PRO20215