OGA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human OGA wild-type allele is located in the vicinity of 10q24.32 and is approximately 34 kb in length. This allele, which encodes protein O-GlcNAcase, is involved in the removal of N-acetylglucosamine (GlcNAc) moieties from O-glycosylated proteins. A translocation t(1;10)(p22;q24) which fuses this gene and the TGFBR3 gene may be involved in some low-grade spindle cell mesenchymal neoplasms.

**Synonyms:** - HEXC - Hyaluronidase in Meningioma Gene - KIAA0679 - MEA5 - MGEA5 - Meningioma Expressed Antigen 5 (Hyaluronidase) Gene - Meningioma-Expressed Antigen 5 Gene - NCOAT - O-GlcNAcase wt Allele