t(1;10)(p22;q24)

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A cytogenetic abnormality that refers to the translocation of the short arm (p22) of chromosome 1 and the long arm (q24) of chromosome 10. It is associated with TGFBR3/OGA (MGEA5) fusions and some cases of pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts, hemosiderotic fibrolipomatous tumor (HFLT), myxoinflammatory fibroblastic sarcoma (MIFS) and hybrid HFLT/MIFS.