FOXN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FOXN1 wild-type allele is located in the vicinity of 17q11.2 and is approximately 33 kb in length. This allele, which encodes forkhead box protein N1, is involved in skin keratinization, T-cell differentiation and maintenance and development and maintenance of the thymus. Mutation of the gene is associated with T-cell immunodeficiency with thymic aplasia, autosomal dominant infantile T-cell lymphopenia (TLIND) and T-cell immunodeficiency with congenital alopecia and nail dystrophy (TIDAND).

**Synonyms:** - FKHL20 - Forkhead Box N1 wt Allele - RONU - Rowett Nude Gene - TIDAND - TLIND - WHN - Winged Helix Nude Gene - Winged-Helix Nude Gene