LAT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LAT wild-type allele is located in the vicinity of 16q13 and is approximately 6 kb in length. This allele, which encodes linker for activation of T-cells family member 1 protein, is involved in signaling pathways modulating immune responses and inflammation. Mutations in the gene are associated with immunodeficiency 52.

**Synonyms:** - IMD52 - LAT1 - Linker for Activation of T Cells wt Allele - Linker for Activation of T Cells, Transmembrane Adaptor Gene - pp36