MVK wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MVK wild-type allele is located in the vicinity of 12q24.11 and is approximately 25 kb in length. This allele, which encodes mevalonate kinase protein, plays a role in cholesterol synthesis. Mutation of the gene is associated with hyperimmunoglobulin D syndrome, mevalonic aciduria and porokeratosis 3.

**Synonyms:** - LH Receptor mRNA-Binding Protein Gene - LRBP - MK - MVLK - Mevalonate Kinase (Mevalonic Aciduria) Gene - Mevalonate Kinase wt Allele - Mevalonic Aciduria Gene - POROK3