LRBA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LRBA wild-type allele is located in the vicinity of 4q31.3 and is approximately 751 kb in length. This allele, which encodes lipopolysaccharide-responsive and beige-like anchor protein, is involved in immune effector molecule trafficking. Mutation of the gene is associated with common variable immunodeficiency-8 with autoimmunity (CVID8).

**Synonyms:** - BGL - CDC4L - CVID8 - LAB300 - LBA - LPS Responsive Beige-Like Anchor Protein wt Allele - LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing Gene - Lipopolysaccharide-Responsive, Beige-Like Anchor Protein Gene - Vesicle Trafficking, Beach and Anchor Containing Gene