RFXAP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RFXAP wild-type allele is located in the vicinity of 13q13.3 and is approximately 10 kb in length. This allele, which encodes regulatory factor X-associated protein, plays a role in the promotion of class II major histocompatibility gene transcription. Mutation of the gene is associated with type II bare lymphocyte syndrome (MHC class II deficiency), complementation group D.

**Synonyms:** - Regulatory Factor X Associated Protein wt Allele