Primary Immune Regulatory Disorder

**Semantic type:** Disease or Syndrome

**Definition:** A group of immune diseases characterized predominantly by immune dysregulation leading to organ-specific autoimmunity, excessive inflammation, and non-malignant lymphoproliferation. Unlike classical primary immunodeficiencies, susceptibility to infections is typically less prominent in these disorders.

**Synonyms:** - PIRD - Primary Immune Dysregulation Disorder - Primary Immune Dysregulation Disorder