Melanoma-Astrocytoma Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An inherited condition caused by autosomal dominant mutation(s) in the CDKN2A gene, encoding cyclin-dependent kinase inhibitor 2A. The condition is characterized by an increased risk of developing melanoma and/or cerebral astrocytoma.

**Synonyms:** - Melanoma and Neural System Tumor Syndrome