Monosomy 7 Myelodysplasia and Leukemia Syndrome 1

**Semantic type:** Disease or Syndrome

**Definition:** An inherited condition caused by autosomal dominant mutation(s) in the SAMD9L gene, encoding sterile alpha motif domain-containing protein 9-like. The condition is characterized by an increased risk of developing myelodysplastic syndrome and acute myelogenous leukemia.

**Synonyms:** - M7MLS1 - Monosomy 7 of Bone Marrow