Activated Polyethylene Glycol/Polyethyleneimine-based Surgical Sealant

**Semantic type:** Biomedical or Dental Material

**Definition:** A surgical sealant composed of activated polyethylene glycol (PEG) and polyethyleneimine (PEI) that can be used to seal tears in the dura during spinal surgery in order to prevent cerebrospinal fluid (CSF) leakage. It may also minimize dural adhesions and scarring by providing a protective shield between the dura and surrounding tissue.

**Synonyms:** - Adherus AutoSpray Dural Sealant - Adherus AutoSpray ET Dural Sealant - Adherus Dural In Situ Polymerizing Sealant - Adherus Dural Sealant