SOS2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SOS2 wild-type allele is located in the vicinity of 14q21.3 and is approximately 114 kb in length. This allele, which encodes son of sevenless homolog 2 protein, is involved in the modulation of Ras signaling. Mutation of the gene is associated with Noonan syndrome 9.

**Synonyms:** - NS9 - SOS Ras/Rho Guanine Nucleotide Exchange Factor 2 wt Allele - SOS-2 - Son of Sevenless (Drosophilia) Homolog 2 Gene - Son of Sevenless Homolog 2 (Drosophila) Gene - Son of Sevenless, Drosophilia, Homolog 2 Gene