Autosomal Recessive Spastic Ataxia-2

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive condition caused by mutation(s) in the KIF1C gene, encoding kinesin-like protein KIF1C. It is characterized by cerebellar ataxia, dysarthria, and variable spasticity of the lower limbs.

**Synonyms:** - Autosomal Spastic Paraplegia Type 58 - SPAX2 - SPG58