EWSR1/SMAD3 Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the EWSR1/SMAD3 fusion gene. This protein is comprised of the N-terminal half of the RNA-binding protein EWS, including the transcriptional activation domain, fused to C-terminal sequences from the mothers against decapentaplegic homolog 3 protein, including part of the linker region and the entire MAD homology 2 (MH2) domain.

**Synonyms:** - EWSR1-SMAD3 Fusion Protein - EWSR1::SMAD3 Fusion Protein - RNA-Binding Protein EWS-Mothers Against Decapentaplegic Homolog 3 Fusion Protein - RNA-Binding Protein EWS/Mothers Against Decapentaplegic Homolog 3 Fusion Protein