Single-Stranded Conformational Polymorphism

**Semantic type:** Nucleotide Sequence

**Definition:** A Single-Stranded Conformational Polymorphism consists of nucleotide sequence variation in the same region of DNA between individuals within a species, or between alleles in an individual, that cause partially denatured DNA fragments to take on different conformations as a result of their nucleotide sequences differences. These conformation differences can be detected through various gel-separation techniques.

**Synonyms:** - Polymorphism, Single-Stranded Conformational - SSCP - SSCP - single-stranded conformational polymorphism