Hyper-Sialylated IgG M254

**Semantic type:** Pharmacologic Substance

**Definition:** A preparation of hyper-sialylated immunoglobulin G (hsIgG) of which IgG is derived from commercially available intravenous immunoglobulin (IVIg), a therapeutic blood product prepared from pooled plasma of healthy donors, with anti-inflammatory and immunomodulating activities that can potentially be used for immune thrombocytopenic purpura (ITP) and other autoimmune and inflammatory diseases. Upon intravenous administration, hsIgG M254 enhances the function of IgG and may, compared to conventional IVIg, have increased anti-inflammatory and immunomodulating activities.

**Synonyms:** - Hyper-Sialylated Immunoglobulin G M254 - M 254 - M-254 - M254 - hsIgG M254