Activating BRAF NP_004324.2:p.V600X

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the valine at position 600 of the serine/threonine-protein kinase B-raf protein to another amino acid that results in constitutive activation of both serine/threonine-protein kinase B-raf and its downstream signaling pathways.

**Synonyms:** - Activating BRAF Codon 600 Mutation - Activating BRAF NP_004324.2:p.Val600 Mutation - Activating BRAF NP_004324.2:p.Val600Xxx - Activating BRAF V600 Mutation - Activating BRAF V600 Protein Variation - Activating BRAF V600X - Activating BRAF V600X Mutation - Activating BRAF p.V600 Mutation - Activating BRAF p.V600X - Activating BRAF p.Val600 Mutation - Activating BRAF p.Val600Xxx - Activating Serine/Threonine-Protein Kinase B-raf Protein V600 Mutation - Activating Serine/Threonine-Protein Kinase B-raf Protein V600 Protein Variation - Activating Serine/Threonine-Protein Kinase B-raf Protein V600X - Activating Serine/Threonine-Protein Kinase B-raf Protein Val600 Mutation - Activating Serine/Threonine-Protein Kinase B-raf Protein Val600Xxx - BRAF Class I Alteration - BRAF Class I Mutation - Class I BRAF Alteration - Class I BRAF Mutation