Human Coronavirus 229E

**Semantic type:** Virus

**Definition:** An alphacoronavirus, first isolated in 1966, that is believed to have originated from African hipposiderid bats and utilizes aminopeptidase N as its major receptor. It is associated with respiratory infections in humans, particularly the common cold, and may have neuroinvasive properties.

**Synonyms:** - Coronavirus 229E - HCoV-229E - HUMAN CORONAVIRUS 229E