Petadeferitrin

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable iron-chelating agent and derivative of desferrithiocin, with iron chelating and protective activities in diseases of iron overload. Upon oral administration, petadeferitrin targets, binds to and chelates free iron. This induces the excretion of iron, prevents iron accumulation and prevents cellular and/or tissue damage associated with iron overload.

**Synonyms:** - (4S)-4,5-Dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic Acid - Chelating Agent SP-420 - Iron Chelating Agent SP-420 - Iron Chelator SP-420 - PETADEFERITRIN - SP 420 - SP-420 - SP420