Transducin Beta-Like Protein 1 Family

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A family of comprised of two proteins that are encoded by similar genes on the X and Y chromosomes and are found in nuclear receptor corepressor protein complexes (NCoR/SMRT), which regulate nuclear receptor-dependent transcriptional repression. Transducin beta-like protein 1 (TBL1) family members may recruit the 19S proteasome complex to NCoR/SMRT complexes and promote complex degradation.

**Synonyms:** - TBL1 - TBL1 Family Protein - Tbl-1 - Transducin Beta-Like 1 - Transducin Beta-Like Protein 1