FN1/FGFR1 Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the FN1/FGFR1 fusion gene. This protein is comprised of the signal peptide and the N-terminal repeats required for cell surface binding, ECM incorporation, fibril formation, and binding of collagen, fibrin, and fibronectin of the fibronectin protein fused to the C-terminal sequences from the fibroblast growth factor receptor 1 (FGFR1) protein, including two of the three extracellular ligand-binding immunoglobulin-like C2 domains, the transmembrane domain and the intracellular tyrosine kinase domain.

**Synonyms:** - FN1-FGFR1 Fusion Protein - FN1::FGFR1 Fusion Protein - Fibronectin 1-Fibroblast Growth Factor Receptor 1 Fusion Protein - Fibronectin 1/Fibroblast Growth Factor Receptor 1 Fusion Protein - Fibronectin-Fibroblast Growth Factor Receptor 1 Fusion Protein - Fibronectin/Fibroblast Growth Factor Receptor 1 Fusion Protein