Triple-Class Refractory Multiple Myeloma

**Semantic type:** Neoplastic Process

**Definition:** A multiple myeloma that is resistant to three classes of therapeutic agents, including proteasome inhibitors, immunomodulatory agents, and monoclonal antibodies.

**Synonyms:** - Triple-Class Refractory Plasma Cell Myeloma - Triple-Class Refractory Plasma Cell Myeloma