Genetic Predisposition to Non-Syndromic Wilms Tumor

**Semantic type:** Finding

**Definition:** A genetic predisposition to Wilms tumor due to germline mutation(s) in the REST, TRIM28, or CTR9 genes, encoding RE1-silencing transcription factor, transcription intermediary factor 1-beta, and RNA polymerase-associated protein CTR9 homolog, respectively.