Autologous MG7-pulsed Dendritic Cell Vaccine

**Semantic type:** Cell|Immunologic Factor|Pharmacologic Substance

**Definition:** A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with the human gastric carcinoma-associated antigen MG7, with potential immunostimulatory and antineoplastic activities. Upon administration at the inguinal lymph nodes, autologous MG7-pulsed DC vaccine may stimulate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against MG7-expressing tumor cells, which may result in tumor cell lysis. MG7, a glycosylated protein sequence from the tumor-associated antigen (TAA) carcinoembryonic antigen (CEA), plays a key role in the development of certain tumor cell types.

**Synonyms:** - Autologous MG-7-pulsed Dendritic Cell Vaccine - Autologous MG7-pulsed DC Vaccine - MG-7 Antigen-pulsed Autologous DC Vaccine - MG7-DC Vaccine