C8A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human C8A wild-type allele is located in the vicinity of 1p32.2 and is approximately 63 kb in length. This allele, which encodes complement component C8 alpha chain protein, plays a role in complement-mediated cell lysis. Mutation of the gene is associated with type 1 C8 deficiency.

**Synonyms:** - Complement C8 Alpha Chain wt Allele - Complement Component 8, Alpha Polypeptide Gene - Complement Component 8, Alpha Subunit Gene