UNC93B1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human UNC93B1 wild-type allele is located in the vicinity of 11q13.2 and is approximately 13 kb in length. This allele, which encodes protein unc-93 homolog B1, plays a role in transport of a subset of certain toll-like receptors from the endoplasmic reticulum to endolysosomes. Mutation of the gene is associated with susceptibility to herpes simplex infection-induced encephalitis type 1.

**Synonyms:** - IIAE1 - UNC93 - UNC93, C. elegans, Homolog of, B1 Gene - UNC93B - Unc-93 Homolog B1 (C. elegans) Gene - Unc-93 Homolog B1, TLR Signaling Regulator wt Allele - Unc-93B1 - Unc93 (C. elegans) Homolog B1 Gene - Unc93 Homolog B1 Gene - Unc93 Homolog B1, TLR Signaling Regulator Gene