Autologous Prostate Cancer-specific Antigens-pulsed Dendritic Cells Cellgram-DC-PC

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous PC-specific antigens-pulsed DCs injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing the antigens, resulting in tumor cell lysis.

**Synonyms:** - Autologous Dendritic Cells Cellgram-DC-PC Pulsed with Prostate Cancer-specific Antigens - Autologous Prostate Cancer-specific Antigens-pulsed DCs Cellgram-DC-PC - Cellgram-DC-PC