Activating GSK3B Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the GSK3B gene that results in constitutive activation of both glycogen synthase kinase-3 beta and its downstream signaling pathways.

**Synonyms:** - Activating GSK3B Mutation - Activating Glycogen Synthase Kinase 3 Beta Gene Mutation - GSK3B Activating Gene Mutation - GSK3B Activating Mutation - GSK3B Gain of Function Gene Mutation - GSK3B Gain of Function Mutation - Gain of Function GSK3B Gene Mutation - Gain of Function GSK3B Mutation