Hydroxymethylglutaryl-CoA Synthase, Cytoplasmic

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Hydroxymethylglutaryl-CoA synthase, cytoplasmic (520 aa, ~57 kDa) is encoded by the human HMGCS1 gene. This protein plays a role in the condensation of acetyl-Coenzyme A with acetoacetyl-CoA to form hydroxymethylglutaryl-CoA (HMG-CoA).

**Synonyms:** - 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase - 3-Hydroxy-3-Methylglutaryl-Co A Synthase 1 - EC 2.3.3.10 - HMG-CoA Synthase - HMG-CoA Synthase 1 - HMGCS1