Inactivating ERCC1 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the ERCC1 gene that either inhibits expression or results in the translation of an inactive DNA excision repair protein ERCC-1.

**Synonyms:** - ERCC1 Gene Inactivation - ERCC1 Inactivating Gene Mutation - ERCC1 Inactivating Mutation - ERCC1 Loss of Function Gene Mutation - ERCC1 Loss of Function Mutation - Inactivating COFS4 Gene Mutation - Inactivating ERCC Excision Repair 1, Endonuclease Non-Catalytic Subunit Gene Mutation - Inactivating ERCC1 Mutation - Inactivating Excision Repair Cross-Complementation Group 1 Gene Mutation - Inactivating Excision-Repair, Complementing Defective, In Chinese Hamster, 1 Gene Mutation - Inactivating RAD10 Gene Mutation - Inactivating UV20 Gene Mutation