Inactivating PRKDC Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the PRKDC gene that either inhibits expression or results in the translation of an inactive DNA-dependent protein kinase catalytic subunit protein.

**Synonyms:** - Inactivating DNA-PKcs Gene Mutation - Inactivating DNAPK Gene Mutation - Inactivating DNPK1 Gene Mutation - Inactivating HYRC Gene Mutation - Inactivating HYRC1 Gene Mutation - Inactivating Hyper-Radiosensitivity of Murine SCID Mutation, Complementing 1 Gene Mutation - Inactivating PRKDC Mutation - Inactivating Protein Kinase, DNA-Activated, Catalytic Polypeptide Gene Mutation - Inactivating XRCC7 Gene Mutation - Inactivating p350 Gene Mutation - PRKDC Gene Inactivation - PRKDC Inactivating Gene Mutation - PRKDC Inactivating Mutation - PRKDC Loss of Function Gene Mutation - PRKDC Loss of Function Mutation