Activating LRP6 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the LRP6 gene that results in constitutive activation of both low-density lipoprotein receptor-related protein 6 and its downstream signaling pathways.

**Synonyms:** - Activating ADCAD2 Gene Mutation - Activating LDL Receptor Related Protein 6 Gene Mutation - Activating LRP-6 Gene Mutation - Activating LRP6 Mutation - Activating Low Density Lipoprotein Receptor-Related Protein 6 Gene Mutation - Gain of Function LRP6 Gene Mutation - Gain of Function LRP6 Mutation - LRP6 Activating Gene Mutation - LRP6 Activating Mutation - LRP6 Gain of Function Gene Mutation - LRP6 Gain of Function Mutation