CYBA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYBA wild-type allele is located in the vicinity of 16q24.2 and is approximately 8 kb in length. This allele, which encodes cytochrome B-245 light chain protein, plays a role in phagocyte synthesis of superoxide. Mutation of the gene is associated with autosomal recessive chronic granulomatous disease 4.

**Synonyms:** - CGD4 - Cytochrome B Light Chain Gene - Cytochrome B(-245), Alpha Subunit Gene - Cytochrome B(558) Alpha-Subunit Gene - Cytochrome B(558), Alpha Subunit Gene - Cytochrome B, Alpha Polypeptide Gene - Cytochrome B-245 Alpha Chain wt Allele - Cytochrome B-245, Alpha Polypeptide Gene - Flavocytochrome B-558 Alpha Polypeptide Gene - p22 phox - p22-PHOX - p22phox