NCF4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NCF4 wild-type allele is located in the vicinity of 22q12.3 and is approximately 17 kb in length. This allele, which encodes neutrophil cytosol factor 4 protein, is involved in the regulation of NADPH-oxidase activity in phagocytes. Mutation of the gene is associated with autosomal recessive chronic granulomatous disease 3.

**Synonyms:** - NCF - NCF, 40-kD Gene - Neutrophil Cytosolic Factor 4 (40kD) Gene - Neutrophil Cytosolic Factor 4 wt Allele - Neutrophil Cytosolic Factor 4, 40kDa Gene - P40 PHOX - P40-PHOX - P40PHOX - SH3PXD4