NCF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NCF1 wild-type allele is located in the vicinity of 7q11.23 and is approximately 15 kb in length. This allele, which encodes neutrophil cytosol factor 1 protein, plays a role in the regulation of the phagosomal oxidative burst. Mutation of the gene is associated with autosomal recessive chronic granulomatous disease type 1.

**Synonyms:** - CGD1 - Chronic Granulomatous Disease, Autosomal 1 Gene - NCF1A - NOXO2 - Neutrophil Cytosolic Factor 1 (47kD, Chronic Granulomatous Disease, Autosomal 1) Gene - Neutrophil Cytosolic Factor 1 wt Allele - Neutrophil Cytosolic Factor 1, (Chronic Granulomatous Disease, Autosomal 1) Gene - SH3PXD1A - p47 phox - p47-phox - p47phox