ABL Class Rearrangement Positive Ph-Like B Acute Lymphoblastic Leukemia

**Semantic type:** Laboratory or Test Result

**Definition:** A finding indicating that activating rearrangements of an ABL class tyrosine kinase gene (which includes ABL1, ABL2, PDGFRB, and CSF1R) have been detected in a patient with Ph-like B acute lymphoblastic leukemia. This finding is associated with a higher relapse risk and may be amenable to treatment that utilizes tyrosine kinase inhibitors.

**Synonyms:** - ABL Class Fusion Positive ALL - ABL Class Ph-Like B-ALL - ABL Class Rearrangement Positive Ph-Like B-ALL - ABL-Class Fusion Positive - ABL-Class Fusion Positive ALL - ABL-Class Ph-Like B-ALL - Ph-like ABL Class Fusion Positive - Ph-like ABL class - Ph-like ABL-Class Fusion Positive