Activating JAK-STAT Pathway Positive Ph-Like B Acute Lymphoblastic Leukemia

**Semantic type:** Laboratory or Test Result

**Definition:** A finding indicating that JAK-STAT pathway activating mutations or rearrangements have been detected in a patient with Ph-like B acute lymphoblastic leukemia. This finding is associated with a higher relapse risk and may amenable to treatment that utilizes JAK-STAT pathway inhibitors.

**Synonyms:** - Activating JAK-STAT Pathway Positive Ph-Like B-ALL - Gain of Function JAK-STAT Pathway Positive Ph-Like B Acute Lymphoblastic Leukemia - Gain of Function JAK-STAT Pathway Positive Ph-Like B-ALL - JAK-STAT Class Positive Ph-Like B Acute Lymphoblastic Leukemia - JAK-STAT Class Positive Ph-Like B-ALL - Ph-like JAK STAT class