Paclitaxel Poliglumex

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties. The polyglutamate residue increases the water solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Paclitaxel promotes microtubule assembly and prevents microtubule depolymerization, thus interfering with normal mitosis.

**Synonyms:** - CT-2103 - CT-2103 - CT2103 - PACLITAXEL POLIGLUMEX - PG-TXL - Paclitaxel Polyglutamate - Paclitaxel-Polyglutamate Polymer - Poly-L-Glutamic acid-Paclitaxel Conjugate - Polyglutamic Acid Paclitaxel - Xyotax - Xyotax - paclitaxel poliglumex - paclitaxel polyglutamate