HLA-E wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HLA-E wild-type allele is located in the vicinity of 6p22.1 and is approximately 5 kb in length. This allele, which encodes HLA class I histocompatibility antigen, alpha chain E protein, plays a role in the modulation of natural killer cell cytotoxicity.

**Synonyms:** - HLA-6.2 - HLA-E Histocompatibility Type Gene - HLAE - MHC Class Ib Antigen Gene - Major Histocompatibility Complex, Class I, E wt Allele - QA1 - QA1, Mouse, Homolog of Gene