Intellectual Developmental Disorder, X-linked 21/34

**Semantic type:** Mental or Behavioral Dysfunction

**Definition:** An X-linked recessive condition caused by mutation(s) in the IL1RAPL1 gene, encoding interleukin-1 receptor accessory protein-like 1. It is characterized by intellectual disability ranging from moderate mental retardation to high-functioning autism.

**Synonyms:** - MRX21 - MRX34 - Mental Retardation, X-linked 21/34